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常州市存仁生物工程有限公司

BIX02188

BIX02188

Description of:BIX02188
BIX02188 is a MEK5-selective inhibitor with an IC50 of 0.8 ± 1.0 μM.
Theoretical analysis:BIX02188
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Pimasertib(AS703026)

Pimasertib(AS703026)

Description of:AS703026 
AS703026 inhibited growth and survival of MM cells (cell IC50 ranging from 0.005 to 2 µM) and cytokine-indu...
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PD98059

PD98059

Description of:PD98059 
PD98059 is inhibitor of mitogen-activated protein kinase kinase (MAPKK / MEK). PD98059 acts by binding to the inac...
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CI1040

CI1040

Description of:CI1040
CI-1040 is a selective MEK inhibitor (Ki = 300 nM in vitro). CI-1040 suppresses FGF-mediated angiogenesis in vivo and dec...
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Selumetinib (AZD6244)司美替尼

Selumetinib (AZD6244)司美替尼

Description of:AZD6244
AZD6244 potently down-regulated the levels of phospho-ERK1/2 and its downstream effector, p-p70S6K, in the MV4-11 and MO...
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GSK1120212

GSK1120212

Description of:GSK1120212-Trametinib
MEK inhibitor GSK1120212 specifically binds to and inhibits MEK 1 and 2, resulting in an inhibition of gro...
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PD0325901

PD0325901

Description of:PD0325901
 PD0325901 is roughly 500-fold more potent than CI-1040 with respect to its cellular effects on phosphorylation o...
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